Cardinex 40mg/0.4ml Injection | Drug International Ltd.
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Home Medicines Blood Clot Cardinex 40mg/0.4ml Injection

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Cardinex 40mg/0.4ml Injection

Generic: Enoxaparin Sodium

Type: Injection

Pack Size: 1 Pc

Each pre-filled syringe contains:

  • 0.2 ml: Enoxaparin Sodium BP 20 mg (2000 anti-Xa IU)
  • 0.4 ml: Enoxaparin Sodium BP 40 mg (4000 anti-Xa IU)
  • 0.6 ml: Enoxaparin Sodium BP 60 mg (6000 anti-Xa IU)
  • 0.8 ml: Enoxaparin Sodium BP 80 mg (8000 anti-Xa IU)

Enoxaparin Sodium, a low molecular weight heparin (LMWH), exhibits high anti-Xa activity and minimal anti-IIa activity. It prolongs clotting time and prevents clot formation by inhibiting specific clotting factors, primarily in the liver.

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MRP: ৳ 425 5% Off

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✅ Description:

Pack Image of Cardinex 4000 Anti-Xa Injection
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✔️ Cardinex is used for:
  1. Treating deep vein thrombosis (DVT), with or without pulmonary embolism.
  2. Managing unstable angina and non-Q-wave myocardial infarction when combined with aspirin.
  3. Preventing thrombus formation during hemodialysis.
  4. Prophylaxis of venous thromboembolism (VTE) in:
    • Orthopedic or general surgery.
    • Bedridden medical patients with acute illnesses (e.g., cardiac insufficiency, respiratory failure, severe infections, rheumatic diseases).
✔️ Instructions for Self-Administering Enoxaparin Sodium Injection
  • Select a spot on your abdomen's right or left side, at least 5 cm away from your belly button.
  • Avoid areas near scars, bruises, or recent injection sites.
  • Rotate between the left and right sides of your stomach to prevent irritation.
  • Wash your hands thoroughly.
  • Use an alcohol swab or soap and water to cleanse the area. Do not rub the site.
  • Sit or lie in a relaxed position where you can easily see the injection site. Use a recliner or bed with pillows for support if needed.
✔️ Selecting Your Dose
  • Carefully pull off the cap and discard it.
  • Avoid pressing the plunger to expel air bubbles, which may reduce the dose.
  • Do not allow the needle to touch any surfaces.
  • If your syringe has the correct pre-filled dose, no adjustment is needed.
  • For weight-based dosing, adjust by pointing the syringe downward and ejecting excess medicine into a container.
  • Tap the syringe gently while holding it downward to remove any air bubbles.
✔️ Administering the Injection
  • Use the hand you write with, holding the syringe like a pencil.
  • Use your other hand to gently pinch a fold of skin between your thumb and forefinger. Maintain the fold throughout the injection.
  • Hold the syringe at a 90° angle (straight down) and insert the full length of the needle into the skin fold.
  • Press the plunger with your thumb until all the medicine is injected into the fatty tissue.
✔️ After the Injection
  • Do not rub the injection site to prevent bruising.
  • Place the used syringe into a sharps container.
  • Close the container securely and store it out of children’s reach.
  • Follow your doctor’s or pharmacist’s instructions for disposing of the full container and any unused medication.
  • Store the medicine as instructed, away from children and extreme temperatures.
✔️ Agents affecting hemostasis:
  • Medications such as acetylsalicylic acid (aspirin), NSAIDs (e.g., ketorolac), ticlopidine, clopidogrel, dextran 40, glucocorticoids, thrombolytics, anticoagulants, and antiplatelet agents (e.g., glycoprotein IIb/IIIa antagonists) should be discontinued before initiating Cardinex unless strictly necessary.
  • If combined use is required, careful clinical and laboratory monitoring is essential.
✔️ Contraindications
  • Patients with known hypersensitivity to Enoxaparin Sodium, heparin, or other low molecular weight heparins.
  • Conditions with a high risk of uncontrolled hemorrhage, such as recent hemorrhagic stroke or major bleeding.
✔️ Overdose Effects:
  • Overdose effects:
    • May cause hemorrhagic complications.
  • Neutralization:
    • Administer protamine sulfate (1% solution) intravenously.
    • Dosage: 1 mg of protamine sulfate neutralizes 1 mg of Cardinex.
✔️ Side Effects
  • Common:
    • Bleeding (hemorrhage), thrombocytopenia (low platelet count), and elevated liver enzymes (aminotransferase).
    • Pain, bruising, or rash at injection sites.
  • Serious:
    • Cases of neuraxial hematomas with spinal/epidural anesthesia or spinal puncture, potentially cause neurological injury.
✔️ Elderly patients:
  • No dosage adjustment unless renal function is impaired.
✔️ Renal impairment:
  • Moderate to mild impairment (creatinine clearance 30–80 ml/min): No adjustment needed but monitor for bleeding signs.
  • Severe impairment (creatinine clearance <30 ml/min):
    • Prophylaxis: 2000 anti-Xa IU once daily.
    • Therapeutic: 100 anti-Xa IU/kg once daily.
✔️ Hepatic impairment:
  • Use cautiously in hepatically impaired patients.
✔️ Pregnancy & Lactation
  • Pregnancy:
    • Classified as Category B. While no evidence suggests Enoxaparin Sodium crosses the placenta, it should only be used during pregnancy if clearly necessary.
    • Pregnant women with mechanical prosthetic heart valves may have an increased risk of thromboembolism.
  • Lactation:
    • Unknown if excreted in human milk. Consider risks to the nursing infant when deciding whether to discontinue nursing or Enoxaparin.
✔️ Precautions & Warnings
  • Administer subcutaneously for treatment and prophylaxis.
  • Administer intravascularly during hemodialysis.
  • Do not inject intramuscularly.
    • Increased bleeding risk (e.g., impaired hemostasis, peptic ulcers, recent stroke, severe hypertension, diabetic retinopathy).
    • Regularly monitor platelet counts during treatment.
    • Caution when combined with medications affecting hemostasis.
✔️ Storage:
  • Store in a cool, dry place (below 25°C) and protect from light and moisture.
  • Do not refrigerate or freeze.
  • Keep out of the reach of children.
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Check our pricing section for Cardinex 40mg/0.4ml Injection price in Bangladesh. After Submitting Order, You may receive phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.

📦Pricing Information, Availability:
Product Availability & Pricing Notice Please note that pricing, availability, and service offerings are subject to change due to: Market fluctuations, Manufacturer or supplier adjustments, Product discontinuation or temporary unavailability, Advertising errors. All orders depend on stock availability and staff resources. If services are provided on a time-and-materials basis, any shared estimates are for planning purposes only.

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